Clinical Research Services

The Quantum Physics of Wound Healing: Part 2: Thoughts on Quantum Phenomena and Their Relation to Wound Healing

To continue our exploration of the quantum physics of wound healing I want to take a long detour into quantum phenomena (clinicians bear with me, no math involved, I promise). Let’s start with the phenomenon of quantum entanglement first described by Einstein and his...

Does the Frequency of Clinic Visits Affect Outcomes

In our prior blog Prior Belief Systems, Placebos, Nocebos, and Wound Healing we talked about various belief systems in regard to wound care. However, there is another elephant in the room that we have not mentioned and that is the frequency that a patient visits a...
  • Clinical research services: designing, running, and analyzing clinical trials; writing trial protocols
  • Statistical analysis of clinical trial or other studies, data mining of large medical databases
  • Health economic analysis (cost-minimization, cost-effectiveness, cost-utility, cost-benefit, cost consequence; simple discrete event analysis to complex Markov modeling
  • Assistance with IDE submissions (FDA) and other FDA issues and assistance with approval at CMS/MACs or other payers
  • Writing medical manuscripts based on trial or study data
  • Systematic reviews and meta-analysis (simple and complex)
  • Submission of manuscripts to journals, and assistance with reviewers’ comments, and creation of response documents
  • Literature searching and obtaining copies of journal articles
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Quality StatementYour decision to use Strategic Solutions, Inc. will be met with quality procedures from individuals who have the education, experience, techniques and skills to provide you with outstanding personal performance. Originally founded by Bonnie Hibschman and Dr. Marissa Carter, Strategic Solutions, Inc. has a firm commitment to excellence and our dedication to writing/editing the words that you need the most, offer to maximize your potential.


We also are willing to collaborate in research projects. Areas that we already collaborate in include wound care, ophthalmology, cost-effectiveness of medical interventions, evidence-based medicine, oncology and nutrition, and infectious diseases.


Call us! Our office hours are 9 a.m. to 6 p.m. Mountain Time, or e-mail us for a prearranged evening consultation. Phone: 307-587-5352 Address: 1143 Salsbury Av., Cody, WY 82414 Email: info@strategic-solutions-inc.com We realize that our outline will generate individual questions, which might not be answered on this web site. Bear in mind that all projects are different, and we are always happy to discuss your project and fees with you by phone, Email, or letter and quote you a precise price or terms. Our goal is to provide you with personalized service.



Over the last several years we have critiqued hundreds of clinical studies either informally or as part of a systematic review. In every instance we have come across problems — some small, but many that can be regarded as design flaws. We cannot fix design flaws! What we can do, however, is help you plan a study so that it doesn’t have any.

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Health Economics

Health economics is the study of medical procedures, drugs, or devices, in terms of cost and outcomes. Although there are many approaches, the most common is cost effectiveness (CE). In this kind of study, the introduction of a medical procedure, drug, or device is examined in terms of its added cost in relation to an existing procedure, drug, or device. Where possible the “gold standard” or accepted standard is utilized. Likewise, the outcomes are compared between the new and old. The cost of the “new” procedure, drug, or device can be less or more than the accepted standard and outcomes can be better or worse. A variation of cost-effectiveness is cost-benefit, in which the benefit is spelled out in terms of some unit. For example, 30-day mortality could be an outcome and the benefit could be lives saved every year. In wound care, cost per ulcer-free month is a common cost benefit analysis. Cost benefit can also examine just costs. Cost utility avoids awkward units and allows health economic studies to be compared to each other in terms of cost per QALY (quality adjusted life years) or other units. The chief disadvantage of cost utility is that for patients with multiple comorbidities in which one is studying a change in one of them it can be difficult to estimate the change in utility, where utility is a scale of 0 (death) to 1 (perfect health). In health economics one seeks to look at the change in costs and outcomes/benefits/utilities to make a policy decision. Any time one has less cost and better outcomes this is very desirable situation, and it is called dominant. Likewise, more cost and worse benefits are easy to evaluate as undesirable (dominated). However, in cases of more cost but better benefits or lower cost but less benefits, these results must be evaluated by policy makers in the context of many other issues. Learn more from the National Information Center on Health Services Research and Health Care Technology (NICHSR)

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Tel: (+1) 307-587-5352

We can perform…

  • Consulting (for example, is there evidence to perform a credible HE study?)
  • Helping you decide the type of study (cost-minimization, cost-effectiveness, cost-utility, cost-benefit, cost consequence)
  • Obtaining data input
  • Carrying out simple cost effectiveness calculations
  • Carrying out discrete events modeling
  • Carrying out Markov modeling.
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